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PMID: 22 PerettiDBastideARadfordHVerityNMolloyCMartinMGet al

Its ability to cross the blood-brain barrier means it plays an important role in removing toxins, such as mercury, from the brain and other cells

& Ros, J

The treatment is non-invasive and painless

3.1.1 Indoxyl sulfate (IS) Indoxyl sulfate (IS) is classified as a protein-bound uremic toxin, with its biosynthesis originating from tryptophan metabolism: gut microbiota first convert tryptophan into indole, which is then transported to the liver for oxidation and sulfation to form IS (Meyer and Hostetter, 2012)